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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAPGEF6
All Species:
18.18
Human Site:
S746
Identified Species:
57.14
UniProt:
Q8TEU7
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEU7
NP_057424
1601
179407
S746
M
L
D
F
S
N
P
S
D
I
P
D
Q
V
I
Chimpanzee
Pan troglodytes
XP_001161644
1601
179429
S746
M
L
D
F
S
N
P
S
D
I
P
D
Q
V
I
Rhesus Macaque
Macaca mulatta
XP_001101427
1601
179534
S746
M
L
D
F
S
N
P
S
D
I
P
D
Q
V
I
Dog
Lupus familis
XP_849936
1459
165157
V631
R
G
D
Q
I
M
E
V
N
G
Q
N
F
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG7
1138
126080
L310
G
V
I
K
Q
R
R
L
P
D
Q
L
S
K
L
Rat
Rattus norvegicus
NP_001100473
1606
179816
S746
M
L
D
F
S
N
P
S
D
I
P
D
Q
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510849
1610
181536
S777
M
L
D
F
S
N
P
S
D
I
P
D
Q
V
I
Chicken
Gallus gallus
XP_420387
1661
185877
P785
I
L
D
F
N
T
T
P
D
L
P
D
Q
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.3
78.6
N.A.
42.1
90.8
N.A.
78.7
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99
83
N.A.
51.2
95.1
N.A.
86.6
73.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
100
N.A.
100
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
13.3
100
N.A.
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
88
0
0
0
0
0
75
13
0
75
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% E
% Phe:
0
0
0
75
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
13
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
13
0
13
0
0
0
0
63
0
0
0
0
63
% I
% Lys:
0
0
0
13
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
75
0
0
0
0
0
13
0
13
0
13
0
0
25
% L
% Met:
63
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
63
0
0
13
0
0
13
0
0
13
% N
% Pro:
0
0
0
0
0
0
63
13
13
0
75
0
0
0
0
% P
% Gln:
0
0
0
13
13
0
0
0
0
0
25
0
75
0
0
% Q
% Arg:
13
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
63
0
0
63
0
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
0
13
0
0
0
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _